Title : BI metalic oxide (Cu&Zn) green synthesis and phytochemical characterization in Curcuma Aromatica
Medicinal plants or their extracts have been used by humans since time immemorial for different ailments and have provided valuable drugs. In recent years, nanotechnology research is emerging as cutting edge technology interdisciplinary with physics, chemistry, biology, material science and medicine. Since few decades ago, the advances in nanoparticles technology have played a remarkable role in medical, pharmaceutical and textile industries. Metal nanoparticles like silver, zinc and gold have been used as therapeutic agents in medical institutes for some years. Curcumin is an active component of turmeric plant; it is responsible for its characteristic yellow color and therapeutic potential. Curcumin is of considerable interest because of its antioxidant, anti-inflammatory, antimicrobial and anticancer activities. Biosynthesis of clean, biocompatible, nontoxic and environmental-friendly nanoparticles produced both extracellularly and intracellularly deserves merit. Curcuma aromaticaSalisb. (C. aromatica) is known wild turmeric in English, “janglihaldi” in Hindi, and “Yu Jin” in Chinese in tamil “kasturiManjal” and “kaatuManjal”. It is mentioned as ‘Vanaharidra’ in Ayurveda. The medicinal properties of this plant are being used in many traditional systems of medicines like Ayurveda and Unani. It is also one of the ingredients of many herbal medicines used in China and other South East Asian countries. It is commonly used as a coloring and flavoring agent, as well as in many traditional medicines in Southeast Asian countries. The rhizomes of C. aromatic are used in traditional medicine for eliminating blood stasis, delaying the ageing process, pain relief, and protecting against liver diseases, the rhizomes of C. aromatic are used internally as a tonic and carminative, while being topically applied for various skin ailments, sprains, bruises, as an antidote for snake venom, and also to enhance complexion. The Phytochemical screening of Curcuma aromatic methanolic extract showed the various phytochemicals like, Flavonoids, phenols, tannins. The quantitative analysis exhibited high amount of Flavonoids. The reduction of Copper ions was monitored by UV-Vis Spectrophotometer for the metal ions stability. The characterization of (CuNps) by UV-Spectrophotometer from the range 200-1100 and absorption peak between 200- 400 nm the presence of ZnNps. The FTIR spectral analysis provided a valid note on chemical nature on the phytoconstituent of Curcuma aromatic (wide range functional groups). The structural elucidation of Curcuma aromatic confirmed with GC-MS analysis of (R)-1-Methyl-4-(6-methylhept-5-en-2-yl) cyclohexa-1,4-diene, 1, 3-Cyclohexadine, 5-(dimethyl-4-hexenyl)-2-methyl-, [S-(R*,S*)]. Curcuma aromatic possess enriched source of phytocompounds which is noted to be of therapeutic value.